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Mako SmartRobotics is Stryker's robotic-arm assisted platform for joint replacement and the dominant robot in orthopedics, with over 3,000 systems installed in 47+ countries and more than 2.5 million procedures performed. It pairs 3D CT-based planning with a haptically bounded robotic arm across five applications: total knee, total hip, partial knee, spine and shoulder. The next-generation Mako 4 began rolling out in 2025-2026.
- More than 2.5 million Mako procedures performed globally over 20 years of robotic-arm assisted surgery [source]
- Installed base surpassed 3,000 systems after a record Q4 2025 [source]
- Next-generation Mako 4 unveiled at AAOS 2025; one system spans multiple orthopedic specialties [source]
Specifications
| Specification | Value | Confidence | Source |
|---|---|---|---|
| Surgical applications | Total knee, total hip, partial knee, spine, shoulder | verified | stryker.com (2026-09-01) |
| Planning | 3D CT-based preoperative planning | verified | stryker.com (2026-09-01) |
| Robotic control | Robotic-arm assisted execution with AccuStop haptic technology | verified | stryker.com (2026-09-01) |
| Procedures performed | 2.5 million+ procedures | verified | stryker.com (2026-09-01) |
| Installed base | 3,000+ systems | reported | fool.com (2026-09-01) |
| Countries with installs | 47+ countries | verified | stryker.com (2026-09-01) |
| Camera | FP8000 wide field-of-view camera with Q Guidance System displays | verified | stryker.com (2026-09-01) |
| US adoption | Over two-thirds of US knee replacements and over one-third of US hips performed on Mako (exiting 2025) | reported | fool.com (2026-09-01) |
Every spec is cited to its source with a retrieval date. verified = manufacturer-published · reported = reputable press/analyst. Verify with the manufacturer before purchase decisions.
Change timeline
- milestone Installed base tops 3,000 systems; revision hip, spine and shoulder applications slated for Mako 4 in mid-2026 [source]
- announcement Next-generation Mako (Mako 4) unveiled at AAOS 2025 [source]
- acquisition Stryker agrees to acquire MAKO Surgical for $1.65 billion [source]
- milestone First MAKOplasty partial knee procedure performed [source]
Our take
Mako is the safest bet in orthopedic robotics: unmatched procedure volume, a deep evidence base and now majority share of US robotic knees. The trade-off is ecosystem lock-in, since Mako is optimized for Stryker implants, and the newer spine and shoulder applications are still ramping compared with the mature knee and hip workflows. Hospitals weighing Zimmer Biomet's ROSA or Smith+Nephew's CORI usually decide based on their implant vendor relationship.
Best suited for
- Total and partial knee replacement
- Total hip replacement, with revision hip launching on Mako 4
- Spine procedures
- Shoulder arthroplasty
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Mako SmartRobotics: common questions
How much does a Stryker Mako robot cost?
Stryker does not publish pricing. Press reports have cited upwards of $1 million per system, with reseller estimates around $0.8-1.4M, plus per-application software licenses and disposables.
How many Mako systems are installed?
Over 3,000 systems worldwide as of Stryker's Q4 2025 earnings, across more than 47 countries.
What surgeries can Mako do?
Five applications: total knee, partial knee, total hip, spine and shoulder. Revision hip, spine and shoulder are launching on the new Mako 4 in mid-2026.
What is Mako 4?
The fourth-generation Mako system, unveiled at AAOS in March 2025. Stryker positions it as one system able to handle more procedures across specialties, and is launching its newest applications on it.
Mako vs ROSA vs CORI: how do they differ?
All three are orthopedic surgical robots tied to their maker's implants: Mako (Stryker) uses CT-based planning with a haptic-bounded arm, ROSA (Zimmer Biomet) and CORI (Smith+Nephew) use imageless or optional-imaging workflows. Mako has the largest installed base.
Sources
- Stryker — stryker.com, retrieved 2026-09-01
- The Motley Fool (Stryker Q4 2025 earnings call transcript) — fool.com, retrieved 2026-09-01
- MassDevice — massdevice.com, retrieved 2026-09-01
- Stryker Investor Relations — investors.stryker.com, retrieved 2026-09-01
- Wikipedia — en.wikipedia.org, retrieved 2026-09-01
- MedCity News — medcitynews.com, retrieved 2026-09-01
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